Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts

Saturday, June 14, 2014

Vizsla Study on Neutering and Cancer

Full article here:   Vizsla study on Cancer and Neutering

New Evidence Shows Link Between Spaying, Neutering and Cancer

June 13, 2014

By Dr. Becker
A recent study raises even more questions about traditional spay/neuter practices for U.S. dogs.
The study, titled "Evaluation of the risk and age of onset of cancer and behavioral disorders in gonadectomized Vizslas,"1 was conducted by a team of researchers with support from the Vizsla Club of America Welfare Foundation. It was published in the February 1, 2014 issue of the Journal of the American Veterinary Medical Association.
Like previous research on Rottweilers and Golden Retrievers, the results of the Vizsla study are a call to action to take a closer look at current neutering recommendations.

Vizsla Study Results

The Vizsla study involved 2,505 dogs, and reported these results:
  • Dogs neutered or spayed at any age were at significantly increased risk for developing mast cell cancer, lymphoma, all other cancers, all cancers combined, and fear of storms, compared with intact dogs.
  • Females spayed at 12 months or younger, and both genders neutered or spayed at over 12 months had significantly increased odds of developing hemangiosarcoma, compared with intact dogs.
  • Dogs of both genders neutered or spayed at 6 months or younger had significantly increased odds of developing a behavioral disorder, including separation anxiety, noise phobia, timidity, excitability, submissive urination, aggression, hyperactivity, and/or fear biting. When it came to thunderstorm phobia, all neutered or spayed Vizslas were at greater risk than intact Vizslas, regardless of age at neutering.
  • The younger the age at neutering, the earlier the age at diagnosis with mast cell cancer, cancers other than mast cell, hemangiosarcoma, lymphoma, all cancers combined, a behavioral disorder, or fear of storms.
  • Compared to intact dogs, neutered and spayed dogs had a 3.5 times higher risk of developing mast cell cancer, regardless of what age they were neutered.
  • Spayed females had nine times higher incidence of hemangiosarcoma compared to intact females, regardless of when spaying was performed, however, no difference in incidence of this type of cancer was found for neutered vs. intact males.
  • Neutered and spayed dogs had 4.3 times higher incidence of lymphoma (lymphosarcoma), regardless of age at time of neutering.
  • Neutered and spayed dogs had five times higher incidence of other types of cancer, regardless of age of neutering.
  • Spayed females had 6.5 times higher incidence of all cancers combined compared to intact females, and neutered males had 3.6 times higher incidence than intact males.

Go to link at top for complete article.

Thursday, June 30, 2011

DNA - Vizslas and Cancer Research

The CHCC (Canine Hereditary Cancer Consortium) is an unprecedented alliance of researchers, veterinarians, physicians and dog owners who are taking advantage of new genetic resources and technologies to learn how the DNA of dogs affected with cancer varies from that of the DNA of healthy, unaffected dogs.
 
No dogs are kept for research; we use only samples from dogs with naturally occurring disease. This research is funded by the National Cancer Institute as well as by corporate sponsorship.


Vizslas are currently included in two of our studies: melanoma and lymphoma. Samples from affected dogs stored at the CHIC repository have been utilized, along with samples submitted by Vizsla owners directly from their affected dogs.

All samples are strictly confidential; no identifying information about dogs or owners is ever released or published.


We also need samples from healthy Vizslas who do NOT have either melanoma or lymphoma, to serve as controls. We will be happy to send buccal (cheek brush) DNA collection kits at owners’ request. The kits are very user friendly, easy to do at home, and include prepaid return mailers.

To participate in the study, please email the following information to Dr. Roe Froman DVM :

Roe.Froman@vai.org




Owner’s name:
Address:

Email:

Names of your pure bred vizslas available for cheek swab sampling


Your participation is needed to help us develop new genetic screens, diagnostic tests, and treatments for canine cancers, as well as helping us to gain insight into the biology of human disease. Your help will be greatly appreciated.

 Last year, I participated in the DNA testing of "the pointing gene" by the same group in Ann Arbor, Michigan.

http://redbirddog.blogspot.com/2010/04/looking-for-pointing-gene.html

Very good people who have great love for our canine companions.  Do it if you can.